Mayo Clinic Performs Record Number of Organ Transplants

Mayo Clinic Transplant achieved the highest annual transplant volume in its history in 2025 by performing 2,065 solid organ transplants, according to data from the Organ Procurement and Transplantation Network (OPTN). 

The new record surpasses 2,006 transplanted solid organs in 2024 and 1,952 in 2023, reflecting Mayo Clinic’s dedication to saving more lives through continued advances in transplantation driven by new research, technology and innovation. The record volume is encouraging, as the number of patients waiting on the national transplant list remains daunting. More than 109,000 people in the United States are currently waiting for lifesaving organs, according to OPTN data. To meet this need, Mayo Clinic teams are advancing the science and delivery of transplantation through initiatives such as: exploring the use of stem cells to prevent organ rejection; using normothermic machine perfusion to improve organ preservation; expanding living donor paired exchange programs; and researching artificial intelligence to transform organ transplants.
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